Typical problems with resource assignment and manpower in project management include:

1. **Resource Overload**: Assigning too many tasks or projects to a single resource can lead to burnout and decreased productivity.
2. **Resource Underutilization**: Conversely, some resources might not be utilized effectively, leading to wasted potential and inefficiency.
3. **Skill Mismatch**: Assigning tasks to resources who lack the necessary skills can result in poor quality work and delays.